News archive

86 stories in this category

ScienceDaily · 27 Oct 2026 · Aging

Immature neurons looked different in people who stayed sharp past 80

ScienceDaily reported on 27 October 2026 a Netherlands Institute for Neuroscience study in Cell Stem Cell. Donated brain tissue from the Netherlands Brain Bank was compared across people without detectable brain pathology, people who had Alzheimer’s dementia, and people whose brains showed Alzheimer’s pathology but who had stayed cognitively well. Immature neurons were still present at an average age over 80 in all three groups. The count difference was smaller than the team expected. In the resilient group, those cells showed more signs of survival programs and lower signals tied to inflammation and cell death. Sex was not reported. This is a tissue study, not proof that the brain is making new neurons or that any therapy produces resilience. Not medical advice.

Read at ScienceDaily →Our summary♡ Save

• 60+
• Cognitive / dementia research

• study
• cognition
• inflammation

ScienceDaily · 26 Oct 2026 · Aging

Seven Mayo papers map senescent cells, including a tomato compound in mice

ScienceDaily reported on 26 October 2026 a Mayo Clinic package of seven papers, several in Nature journals, on senescent cells that stop dividing but keep releasing inflammatory signals. The set includes a gene-pattern tool, SenMayo, tested in part on bone biopsies from older adults, and work on mitochondrial routes to that inflammatory signal. In older mice, senolytic approaches, a tomato compound called tomatidine, and genetic targeting were linked to lower inflammation and, depending on the experiment, better frailty measures or cognitive-task scores. A blood marker, IL-23R, is proposed only as a research measure. These are lab and mouse findings plus a gene-set methods paper, not a reason to use tomato compounds or senolytic drugs. Not medical advice.

Read at ScienceDaily →Our summary♡ Save

• Cognitive / dementia research
• Medicine
• Aging

• study
• cognition
• inflammation

EurekAlert · 26 Oct 2026 · Aging

An extra year of school lined up with fewer dementia diagnoses decades later

On 26 October 2026, University of Southern California researchers described a study of the 1972 British reform that raised the school-leaving age from 15 to 16. The share staying until at least 16 rose by 14 percentage points. In UK Biobank records followed through age 65, people born just after the cutoff were less likely to have a dementia diagnosis, including among those with high genetic risk. This is a schooling comparison in existing health records. Not medical advice.

Read at EurekAlert →Our summary♡ Save

• Cognitive / dementia research
• Aging

• study
• cognition

EurekAlert · 22 Oct 2026 · Aging

A review frames the months after birth as a window in maternal aging

On 22 October 2026 Mass General Brigham described a Trends in Endocrinology & Metabolism review, not a new cohort. The authors pull together studies in which biological age measures rise during pregnancy and partly fall afterward, across wearable data, brain imaging, blood scores, and DNA-methylation clocks, in work from Europe, the United States, and the Philippines. Recovery in those studies ran from a few months to a year or more and appeared to vary with pre-pregnancy weight, breastfeeding, and possibly sleep. They propose that a next pregnancy during that window could interrupt recovery, and they say that idea still needs decades-long tests. The release repeats the World Health Organization spacing guidance already in place since 2005 and says this paper does not change current medical advice. Age bands were not pooled into one number. Not medical advice.

Read at EurekAlert →Our summary♡ Save

• Women
• Metabolic / glucose
• Cognitive / dementia research
• Aging

• commentary
• sleep
• cognition

Aging Cell · 22 Oct 2026 · Aging

In the lab, blood-cell precursors from an 80-year-old became neural stem cells whose molecular age read under 20

Study (laboratory, cells from one donor age). Lea Jessica Berg, Oliver Brüstle, and colleagues report in Aging Cell (2026; 25(10); DOI 10.1111/acel.70751). ScienceDaily carried it on 21 Oct 2026. They converted human red-blood-cell precursors directly into neural stem cells, skipping the pluripotent stage. Epigenetic clocks on cells from an 80-year-old donor moved to a signature under 20. The write-up says about 60 years of that shift was visible by about 50 days, and the change could be followed for more than 100 days. The authors describe a model for watching cellular rejuvenation, not a treatment that makes a person younger. Cells from one donor in a dish are not evidence about human healthspan. Not medical advice.

Read at Aging Cell →Our summary♡ Save

• Aging
• Longevity

• study
• longevity

Frontiers in Aging · 22 Oct 2026 · Aging

Functional status following the COVID-19 lockdown and five-year survival among older adults with pre-existing functional dependence: a cohort study

IntroductionLockdown for the COVID-19 pandemic in Spain (14 March 2020 - 21 June 2020) represented a situation of prolonged stress; this study analyzed the association between changes in functional status observed after the lockdown and 5-year survival.Materials and MethodsA prospective longitudinal cohort study conducted between 22 June 2020, and 30 June 2025. As of 1 March 2020, Orcasitas (Madrid, Spain) had 150 re

Read at Frontiers in Aging →Our summary♡ Save

• 60+
• Aging

• original research
• study

ScienceDaily · 21 Oct 2026 · Aging

Too much RNA can starve cells of energy, scientists discover

Scientists have uncovered an unexpected danger lurking inside cells: too much RNA can damage the structures responsible for producing energy. A new study found that excess RNA, including the normally essential messenger RNA (mRNA), can directly disrupt mitochondria without relying on the immune system. The discovery could help explain how viral infections and certain aging-related diseases damage cells.

Read at ScienceDaily →Our summary♡ Save

• Aging

• news
• study

ScienceDaily · 21 Oct 2026 · Aging

Rejuvenation breakthrough: Scientists reverse 60 years of aging in human cells

Scientists have turned blood cells from an 80-year-old into neural stem cells with a molecular age of less than 20, effectively reversing more than 60 years of cellular aging in the laboratory. The discovery offers a new way to investigate how cells become younger and could help researchers better understand age-related diseases such as Alzheimer's.

Read at ScienceDaily →Our summary♡ Save

• Cognitive / dementia research
• Aging

• cognition

Columbia University / Nature Aging · 20 Oct 2026 · Aging

In mice carrying APOE4, fibronectin around brain vessels was nearly double, and lowering it tightened the barrier

Study (human tissue plus animals, not a treatment trial). Caghan Kizil and colleagues at Columbia University Irving Medical Center report in Nature Aging (2026; 6(9):1901; DOI 10.1038/s43587-026-01204-0). ScienceDaily carried it on 19 Oct 2026. Some people who carry APOE ε4, a common Alzheimer's risk variant present in about one in five people, stay mentally sharp into their 80s. Earlier work from the same group found a rare fibronectin (FN1) mutation in some of those carriers. This paper says APOE ε4 pushes fibronectin to build up around brain blood vessels. Mice engineered with human APOE ε4 had nearly twice as much fibronectin in the brain as mice with APOE ε3, and their blood-brain barrier was leakier. Raising human fibronectin in astrocytes was enough to make the barrier more permeable. Lowering it improved barrier function. The same pattern showed up in human Alzheimer's tissue, cerebrospinal fluid, stem-cell vessel models, zebrafish, and mice. Excess fibronectin was tied to abnormal integrin and focal adhesion kinase signals that scramble VEGF, HBEGF, and IGF1 communication. Fibronectin also has normal jobs in tissue repair, so blocking it everywhere is not a ready therapy. Not medical advice.

Read at Columbia University / Nature Aging →Our summary♡ Save

• 60+
• Cognitive / dementia research
• Aging

• cognition
• genetics
• study

ScienceDaily · 20 Oct 2026 · Aging

Your aging brain may be trading memory for something more valuable

The aging brain may be undergoing a remarkable transformation rather than simply losing its abilities, shifting its focus from remembering details to understanding the bigger picture. Scientists suggest this change could be an evolutionary adaptation that helps older adults develop wisdom and share decades of knowledge with younger generations.

Read at ScienceDaily →Our summary♡ Save

• 60+
• Cognitive / dementia research
• Aging

• cognition

EurekAlert · 20 Oct 2026 · Aging

A review maps a nutrient-sensing pathway in aging research

On 20 October 2026 a review in the journal Aging, first published in September, was highlighted as a map of how the mTOR pathway coordinates nutrient sensing and cellular stress responses. The authors discuss lifestyle and laboratory interventions that converge on that pathway, and they note that suppressing it too hard may have downsides for repair. This is a review, not a human trial. Not medical advice.

Read at EurekAlert →Our summary♡ Save

• Aging
• Longevity

• commentary
• longevity
• study

ScienceDaily · 19 Oct 2026 · Aging

"Mind-blowing" Alzheimer’s breakthrough: Two hours of sleep restored without clearing brain plaques

Scientists have uncovered an unexpected culprit behind sleep loss in Alzheimer’s disease: overactive immune cells in the brain. By temporarily removing these cells, researchers restored more than two hours of sleep per day in mice, revealing a promising new target for treatment.

Read at ScienceDaily →Our summary♡ Save

• Cognitive / dementia research

• sleep
• cognition

VitaLonga is an educational longevity resource, not a pharmacy, clinic, or doctor. Content is not medical advice and is not intended to diagnose, treat, cure, or prevent any disease (DSHEA). Supplements can interact with medications and are not appropriate in every pregnancy or health condition. Consult a licensed clinician, especially if you take medications, are pregnant or nursing, or have a diagnosed condition.