
ScienceDaily · 6 Sept 2026
Popular brain supplement linked to shorter lifespan in men
Study (observational plus Mendelian randomization). Zhao, Sun, Zhang and Ye (Hong Kong and Georgia) analyzed more than 270,000 UK Biobank participants in Aging-US. Higher blood tyrosine tracked with shorter predicted male lifespan—about a year in genetic estimates—while women showed no significant effect. Phenylalanine dropped out after adjusting for tyrosine. The authors did not test tyrosine pills; this is not proof that a focus supplement shortens life. Protein restriction to lower tyrosine is unproven as a longevity tactic and can work against muscle in older adults. Discuss supplements with a clinician.
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