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International Journal of Obesity · 22 Oct 2026 · Nutrition

In an emulated trial of 3,789 postmenopausal women, a hypothetical higher protein intake lined up with less abdominal fat

Study (emulated target trial on existing cohort data, not a feeding experiment). Investigators report in the International Journal of Obesity (2026; 50(3): 609-617; DOI 10.1038/s41366-025-01978-0), published online 9 Jan 2026. They used DXA scans from 3,789 postmenopausal women ages 50 to 79 in the Women's Health Initiative and asked what body composition would have looked like if everyone had kept protein at or above set levels for three years. The women were not randomized to protein doses. The model estimates that holding intake at or above 1.5 grams per kilogram per day, versus no such target, lined up with lower visceral fat (minus 13.1 cm2, 95 percent CI minus 18.9 to minus 7.3), lower subcutaneous abdominal fat (minus 25.3 cm2, minus 39.7 to minus 11.0), lower body-fat percentage (minus 1.0, minus 1.7 to minus 0.3), lower weight (minus 2.5 kg, minus 3.7 to minus 1.2), and a higher lean-soft-tissue percentage (plus 0.9, 0.3 to 1.6). The authors say estimated benefits started around 1.2 grams per kilogram per day. A model of a hypothetical diet is not evidence that eating that much protein produced those changes in a trial. Not medical advice.

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BMC Women's Health · 22 Oct 2026 · Exercise

In 66 women ages 45 to 60, eight weeks of combined exercise cut menopause symptom scores in person and in an app

Study (randomized trial). Investigators report in BMC Women's Health (2026; 26: 297; DOI 10.1186/s12905-026-04457-4), published 25 April 2026. Sixty-six early postmenopausal women ages 45 to 60 were randomized to eight weeks of the same home program delivered face to face (22), through a mobile app (22), or to education only (22). The program was three days a week and mixed walking, resistance work, core work, and balance. Versus education only, menopause symptom scores fell more with face-to-face coaching (Cohen's d minus 1.16) and with the app (d minus 0.76). The gap between the two exercise arms was negligible to small. The paper also reports modest gains in muscle mass and predicted aerobic capacity. It does not include adherence data for the app, which limits that comparison. The upper age is 60, so the older-age tag only just applies. Symptom scores are not a disease treatment. Not medical advice.

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Aging · 22 Oct 2026 · Supplements / medicine

In UK Biobank genetic analyses, higher tyrosine lined up with about 0.9 fewer years of life in men, and not clearly in women

Study (cohort plus Mendelian randomization), not a supplement trial. Jie V. Zhao, Yitang Sun, Junmeng Zhang, and Kaixiong Ye report in Aging (published 3 Oct 2025; PMID 41045493; DOI 10.18632/aging.206326). ScienceDaily carried it on 6 Sep 2026. They used UK Biobank, a cohort recruited at ages 40 to 69. Reports of the paper describe 272,475 participants, including 125,359 men. After the genetic analysis accounted for phenylalanine, higher tyrosine lined up with 0.91 fewer years of life in men (95 percent CI 1.60 to 0.21 fewer). In women the estimate was 0.36 fewer years and the interval crossed zero (0.96 fewer to 0.23 more). Phenylalanine was not tied to lifespan once tyrosine was in the model. Tyrosine is in protein foods and in some focus supplements. The authors' suggestion that lowering a high level might extend life is their reading of a genetic association. This did not test a diet or a pill, and it is not a reason to avoid protein foods. Not medical advice.

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