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Newest story: 14 Nov 2026

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npj Aging · 14 Nov 2026 · Aging

In 774 healthy older adults, lifestyle-linked brain patterns added little for predicting later cognition

A cross-sectional and 4-year analysis of healthy aging, from the 1000BRAINS study, was published online on 14 November 2026. It included 774 healthy older adults (mean age 67.0 years, standard deviation 6.7). The abstract does not give a sex split. Brain features tied to an overall lifestyle profile were compared with features tied to single lifestyle factors for 13 cognitive outcomes. The combined model did best for baseline figural memory, using regions in the salience and ventral attention, default mode, somatomotor, and visual networks. Those models did not consistently beat data-driven models that used only shared brain variation. Adding demographic variables improved prediction. Single lifestyle factors added little. No model reliably predicted cognitive change over 4 years. An observational scan study, not a program test. DOI 10.1038/s41514-026-00558-4. Not medical advice.

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BMC Geriatrics · 14 Nov 2026 · Aging

In 9,316 older adults, a cystatin C kidney reading lined up with higher mortality when creatinine looked normal

A two-cohort analysis of CHARLS and HRS was published online on 14 November 2026. It included 9,316 adults aged 65 years or older whose creatinine-based filtration rate was at least 60 mL/min/1.73 m2. The abstract does not give a sex split. A low cystatin C-based rate, under 60, was present in 3,130 people (33.6 percent). The mortality analysis had 8,384 people and 1,411 deaths. Hazard ratios were 1.44 (95 percent CI 1.19 to 1.74) in CHARLS and 1.62 (95 percent CI 1.39 to 1.89) in HRS. After a further adjustment for physical function, the ratios were 1.26 (95 percent CI 1.02 to 1.55) and 1.34 (95 percent CI 1.06 to 1.70). The same reading lined up with later difficulty in daily activities (hazard ratios 1.10 and 1.28) and with mortality after that difficulty had begun (1.32 and 1.57). Cardiovascular results differed between the two cohorts. An association in aging cohorts. The authors say a small indirect estimate does not show a causal path. DOI 10.1186/s12877-026-08539-8. Not medical advice.

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Scientific Reports · 14 Nov 2026 · Exercise

In 28 overweight young women, resistance training plus breathing practice changed lipids, breathing, and aerobic capacity

A randomized trial was published online on 14 November 2026. Twenty-eight young women with overweight were assigned to resistance training or to the same training plus breathing retraining. The abstract does not give a numeric age range. Sessions were supervised for 8 weeks, 3 times a week, 60 minutes each. Both groups had lower triglycerides, LDL cholesterol, systolic and diastolic blood pressure, central aortic systolic pressure, a second systolic peak, and radial augmentation index, and higher vital capacity, forced vital capacity, maximal voluntary ventilation, forced expiratory volume in 1 second, peak expiratory flow, and VO2peak (p<0.05). The breathing group improved further on anaerobic threshold, peak oxygen pulse, vital capacity, maximal voluntary ventilation, the second systolic peak, and central aortic systolic pressure (p<0.05). Registry ChiCTR2400089050. The abstract does not give the size of each change. A small trial with no inactive comparison group. DOI 10.1038/s41598-026-80091-2. Not medical advice.

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VitaLonga Daily Brief — November 15, 2026

November 15, 2026 · 18:26

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