Aging · 22 Oct 2026
In the lab, blood-cell precursors from an 80-year-old became neural stem cells whose molecular age read under 20
Source: Aging Cell
What the research found
Study (laboratory, cells from one donor age). Lea Jessica Berg, Oliver Brüstle, and colleagues report in Aging Cell (2026; 25(10); DOI 10.1111/acel.70751). ScienceDaily carried it on 21 Oct 2026. They converted human red-blood-cell precursors directly into neural stem cells, skipping the pluripotent stage. Epigenetic clocks on cells from an 80-year-old donor moved to a signature under 20. The write-up says about 60 years of that shift was visible by about 50 days, and the change could be followed for more than 100 days. The authors describe a model for watching cellular rejuvenation, not a treatment that makes a person younger. Cells from one donor in a dish are not evidence about human healthspan. Not medical advice.
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