Human study · Exercise · 21 Sept 2026
Regular exercisers in their twenties showed different blood metabolites and immune cells than sedentary peers
Source: News-Medical
What the research found
Study (cross-sectional). Song and colleagues report in Science Advances on 86 non-obese adults aged 20 to 40 (mean age 28, mean BMI 21.3). Forty people who exercised at least three times a week, meeting about 150 minutes moderate or 75 minutes vigorous, were compared with 46 people who reported no planned exercise. Blood differences involved glucose and lipid metabolism, metabolites consistent with fatty acid oxidation, and antioxidant-related metabolites. Bilirubin, uric acid, and creatinine were higher in the exercise group. Models adjusted for sex and BMI. A women-only look showed similar gene-expression trends. Habit comparison, not a training trial, and muscle mass was not measured. Educational exercise notes.
Evidence level: Human study. A study in people, but an association isn't proof of cause.
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