Clinical trial · Exercise · 4 Sept 2026
A 12-month gym-plus-diet program eased ADT quality-of-life and fatigue in the STAMINA trial
Source: The Lancet Oncology
What the research found
Study (multicentre RCT). STAMINA investigators report in The Lancet Oncology (4 September 2026) that 389 men on androgen-deprivation therapy for prostate cancer were randomized to 12 months of supervised aerobic plus resistance exercise, dietary advice, behavioural support and gym membership versus enhanced usual care (n=311). STAMINA improved FACT-P by 4.5 points (p=0.0004) and FACIT-F fatigue by 1.9 (p=0.0068) at 12 months. Open-label NHS setting. Educational exercise notes, not a cancer treatment.
Evidence level: Clinical trial. This is among the stronger kinds of evidence, but one study rarely settles a question.
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