University of British Columbia / Translational Vision Science & Technology · 11 Oct 2026 · Aging
Study (mouse imaging, not a human treatment). ScienceDaily carried the University of British Columbia account on 11 October 2026. The university materials are dated July 2026. Babishaa Sauntharrajan, Neeru Gupta, Yeni H. Yücel, and colleagues, with the University of Toronto, report in Translational Vision Science & Technology (2026; 15(7):23; doi 10.1167/tvst.15.7.23). Using MRI, near-infrared fluorescence, and microscopy, they put tracer into a space at the back of the mouse eye. Fluid moved through small lymphatic vessels in the choroid, the layer under the retina, out into the tissues around the eye, and reached nearby lymph nodes within minutes. They call the route the posterior ocular lymphatic outflow, or POLO, pathway. Gupta said the retina makes constant waste and that this route may explain how some of it leaves. The release links glaucoma and age-related macular degeneration with fluid, waste, and inflammation at the back of the eye, and says age-related macular degeneration affects about 2.5 million Canadians. It does not show that the pathway works the same way in people, or that it can be boosted as a treatment. Sex and age of the mice are not given. A 2009 front-of-eye lymphatic route by Gupta and Yücel is cited as earlier work, not as this result. Educational notes. This is not an eye treatment.
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