Aging · 14 Oct 2026
Impaired autophagy and lysosome function in human fibroblast aging
Source: Frontiers in Aging
What the research found
BackgroundHuman aging is characterized by a progressive, time-dependent deterioration in physiological and cognitive functioning. Aging is driven by an array of interconnected cellular hallmarks, including genomic instability, mitochondrial dysfunction, telomere attrition, epigenetic alteration and dysfunctional autophagy. Autophagy is a cytoprotective (cellular degradation and recycling) pathway that maintains homeo
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