Human study · Aging · 25 Aug 2026
Sex-specific aging clocks from a large-scale human phenome reveal distinct aging transitions
Source: Nature Aging
What the research found
Study. Under the X-Age Project, researchers profiled 172 routine clinical measures from more than 100,000 adults aged 18–98 in the Multicentric Chinese Aging Study and built sex-specific clinical aging clocks (Nature Aging, 25 Aug 2026; EurekAlert summary 31 Aug 2026). Men showed a metabolic shift around 35–45 years (BMI, triglycerides, cholesterol); women showed a later transition around 55–65 years near menopause. Differences narrowed later in life. Metabolic factors and some tumor-related markers accumulated with age and tracked faster physiological aging. This is a research clock from checkup data, not a diagnostic test VitaLonga can order and not a treatment.
Evidence level: Human study. A study in people, but an association isn't proof of cause.
More aging news
- In middle-aged male mice, an earlier loss of new tumor-fighting immune cells lined up with weaker melanoma control
- A commentary says telomere RNA loops can stall DNA copying and, in some tumors, get used to keep chromosome ends going
- After a long decline, heart-valve death rates in U.S. older adults rose from 2018 to 2023
- In adults over 50 followed for 24 years, a higher body mass index lined up with a faster drop in memory and thinking
- A lab force on bone extended lifespan in older mice through a signal called PEDF