A peanut lipid pattern in blood tracked with a lower chance of type 2 diabetes

What the research found

SciTechDaily reported this on 30 October 2026. Dominguez-Lopez, Schulze, and colleagues, at the German Institute of Human Nutrition and the University of Barcelona, published the work in the American Journal of Clinical Nutrition on 17 September 2026 (DOI 10.1016/j.ajcnut.2026.101527). In the ARISTOTLE feeding trial, 63 healthy adults aged 18 to 33 ate a daily food portion for six months: 25 g of skin-roasted peanuts, or 32 g of peanut butter, or 32 g of a control butter made with peanut oil. The blood pattern they call a peanut lipidomic signature rose in very-long-chain saturated fatty acids, especially lignoceric acid (C24:0) and behenic acid (C22:0), including in ceramides. They then looked at that signature in EPIC-Potsdam, more than 27,000 people, with 774 new cases of type 2 diabetes and 545 cases of cardiovascular disease. The signature was associated with a lower chance of type 2 diabetes, not with cardiovascular disease, and much of the diabetes link was statistically explained by BMI. The feeding trial was in young adults. The diabetes link is from the larger observational cohort, not from an age-band result, so this card is not tagged to one age group. This does not show that peanuts prevent diabetes. Not medical advice.

Evidence level: Human study. A study in people, but an association isn't proof of cause.

Read the original at SciTechDaily