Animal study · Aging · Added 25 Sept 2026
Peripheral adaptive immune remodeling associated with severe hearing loss in older adults: a single-center flow-cytometry study with mouse cochlear transcriptomic context
Source: Frontiers in Aging
What the research found
ObjectiveTo investigate the association between severe hearing loss and systemic immune aging in older adults using participant-level clinical immunophenotyping, and to explore potential inflammatory pathways and cellular contexts using public mouse cochlear transcriptomic data.MethodsWe analyzed a single-center cohort of 76 older adults, classified into normal hearing (NH), mild-to-moderate hearing loss (MMHL), or s
Evidence level: Animal study. Results in animals or cells often don't carry over to people.
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