Human study · Nutrition · 20 Sept 2026
In 92 memory-clinic patients 65 and older, higher polyphenol intake tracked lower odds of MCI
Source: News-Medical
What the research found
Study (cross-sectional). Grasso and colleagues report in Antioxidants (2026; 15(9):1181; doi 10.3390/antiox15091181) on 92 autonomous adults aged 65 or older at a memory clinic in Troina, Italy. People without mild cognitive impairment reported higher intakes of total polyphenols, flavonoids, and lignans than those with MCI. The highest-versus-lowest groups still differed after adjustment for energy, age, sex, education, and smoking, with flavones the strongest flavonoid signal. Total polyphenol intake was not significantly tied to MMSE or MoCA scores, and links to inflammatory markers were weak. Small dietary-recall study without correction for multiple comparisons. Exploratory association, not evidence that a polyphenol pill prevents dementia. Educational nutrition notes.
Evidence level: Human study. A study in people, but an association isn't proof of cause.
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