Supplements / medicine · 14 Nov 2026
In 914 Mexican adolescents, about half had vitamin D deficiency, and girls had lower levels than boys
Source: Pediatric Research
What the research found
A cross-sectional study was published online on 14 November 2026. It included 914 adolescents aged 11 to 18 years in Tlaxcala, Mexico. Median 25-hydroxyvitamin D was 19.8 ng/mL. 44.3 percent were in the insufficiency range and 50.4 percent were in the deficiency range. Girls had lower levels than boys (18.5 versus 22.1 ng/mL, p<0.0001) and a higher deficiency share (62 percent versus 36 percent). A low bone reading (Z score at or below -1) was present in 18.7 percent at the radius and 24.3 percent at the tibia. 25-hydroxyvitamin D lined up with osteocalcin (beta 0.28, p=0.013) and osteopontin (beta 0.28, p=0.034) and inversely with osteoprotegerin (beta -1.86, p=0.050), especially in girls. No clear link was seen with parathyroid hormone, FGF23, RANKL, or the ultrasound bone measures. A one-time blood and ultrasound survey. It is not a dosing guide. DOI 10.1038/s41390-026-05530-2. Not medical advice.
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