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Research · 4 Nov 2026

In culture dishes, a palladium complex used carbon monoxide from cancer cells to form a compound the noncancerous cells did not make

Source: ScienceDaily

What the research found

ScienceDaily dated its page 3 November 2026. The feed clock falls on 4 November in Bangkok. The report covers a Nature Communications paper from Katsunori Tanaka's group at RIKEN. They enclosed a palladacycle in albumin so glutathione would not shut off the palladium catalyst, then exposed cultured human liver, cervical, breast, and lung cancer cells, plus a noncancerous cell line, for 48 hours. Phenanthridinone showed up in the cancer lines and not in the noncancerous line. A later version of the reaction formed a toxic phenanthridinone derivative inside cultured liver cancer cells, and those cells showed damage. In a laboratory blood test, the toxic compound did not form. The authors attribute that to carbon monoxide already bound to hemoglobin. The paper has no animal experiment and no patient series. DOI 10.1038/s41467-026-77616-8. Not medical advice.

Read the original at ScienceDaily

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