Human study · Research · 30 Oct 2026
A stent or an operation did not lift memory scores above usual care in tight carotid narrowing
Source: SciTechDaily
What the research found
SciTechDaily reported this on 30 October 2026. CREST-H, led by Randolph Marshall at Columbia, enrolled 291 people with severe carotid narrowing of at least 70 percent and no related symptoms. Cognition and brain blood flow were measured at the start and at one year. Thinking scores rose slightly in both groups. Adding a stent or an operation was no better for those scores than the care used alone. In the parent CREST-2 trial, adding a stent to that care cut strokes by about half compared with care alone, while an operation to remove the blockage did not. The cognition paper is JAMA, DOI 10.1001/jama.2026.13384. The page used here did not give the journal date. Funding includes NIH R01NS097876, and the parent trial U01NS080168, U01NS080165, and U01NS086872. Age and sex were not stated in the account used here. This is not advice to seek or refuse a procedure. Not medical advice.
Evidence level: Human study. A study in people, but an association isn't proof of cause.
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