Human study · Research · 29 Oct 2026
A ten-marker metabolic score was presented as a health signal at a scientific meeting
Source: EurekAlert
What the research found
This is a meeting report, not a journal paper. A 29 October 2026 FAPESP release describes a talk by Joris Deelen of Leiden University Medical Center at FAPESP Week Netherlands. A score from blood samples of 44,000 volunteers in 12 European cohorts had 5,500 deaths in follow-up. With Brazilian student Gabriela Natalle Lopes, the group cut the score to ten routine blood markers and flipped the sign so a higher number means better health. Deelen said a one-point rise corresponds to an average 14-year delay before a first cardiometabolic disease. That figure is the speaker's claim at a meeting, not a journal result. He also said the score lines up with cognition, lung capacity, and handgrip. Changes in daily habits improved insulin, triglycerides, and body composition mainly when the starting score was below zero, not in the whole group. He described the score as about 40 percent genetic and about 60 percent habits and surroundings. Smoking was called the strongest negative behavior, and being more active lined up with a better score. Sex and exact age bands were not given. Not medical advice.
Evidence level: Human study. A study in people, but an association isn't proof of cause.
More research news
- In mice, fear made hippocampal maps of a safe place and a dangerous place overlap
- In pregnant mice, immune activation at day 12.5 lined up with placental injury and autism-like traits in male fetuses only
- Support cells in brain tissue from 73 people with Parkinson's showed sex differences in energy-gene and myelin-gene activity
- In 10,362 adults, night-to-night swings in sleep timing lined up with a higher risk of serious cardiovascular events
- In a U.S. telephone survey of 442,906 adults, reported cannabis use lined up with higher odds of cardiovascular disease, especially stroke