Human study · Supplements / medicine · 9 Sept 2026
Hormone therapy use may lead to fewer mood disturbances during the menopause transition
Source: EurekAlert
What the research found
Study (observational). A Menopause Society report on a retrospective clinic cohort of 260 women, published in Menopause, found that systemic hormone therapy started for FDA-approved indications was followed by fewer psychological and sleep symptoms. The share with severe mood symptoms fell from 62.3% to 24.6%, with the largest change among those who started with more severe symptoms; response did not differ by psychiatric history, age, menopause stage, or antidepressant use. Association is not a prescription. Hormone therapy is clinician-only. Not medical advice and not a substitute for mental-health care.
Evidence level: Human study. A study in people, but an association isn't proof of cause.
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