Human study · Supplements / medicine · 2 Sept 2026
Healthy ageing shaped by more varied biology than previously thought
Source: News-Medical
What the research found
Study (longitudinal). King’s College London researchers (Julia El-Sayed Moustafa, Kerrin Small and colleagues) report in Science the most comprehensive molecular aging map of its kind: 335 TwinsUK adults followed eight years with repeated blood RNA (~16,000 genes) and hundreds of metabolites. Two healthy people of the same age could show opposite molecular change. Trajectories differed for a cardiac-aging gene (CXCL9) and for TP53 in some people; PFAS “forever chemical” blood levels correlated with shifting profiles. Innate and adaptive immune cells did not age the same way. This is a roadmap paper, not a trial of a longevity supplement and not a diagnosis. Educational biology notes.
Evidence level: Human study. A study in people, but an association isn't proof of cause.
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