Human study · Research · 18 Oct 2026
Scientists uncover 3 key brain pathways linked to lasting depression relief
Source: ScienceDaily
What the research found
Researchers have uncovered three brain pathways linked to lasting improvements in people receiving deep brain stimulation for severe, treatment-resistant depression. They also discovered that patients who failed to improve after two years shared a striking pattern: insufficient stimulation of a crucial brain connection. The findings suggest that millimeters in electrode placement could make a major difference in trea
Evidence level: Human study. A study in people, but an association isn't proof of cause.
More research news
- In mice, fear made hippocampal maps of a safe place and a dangerous place overlap
- In pregnant mice, immune activation at day 12.5 lined up with placental injury and autism-like traits in male fetuses only
- Support cells in brain tissue from 73 people with Parkinson's showed sex differences in energy-gene and myelin-gene activity
- In 10,362 adults, night-to-night swings in sleep timing lined up with a higher risk of serious cardiovascular events
- In a U.S. telephone survey of 442,906 adults, reported cannabis use lined up with higher odds of cardiovascular disease, especially stroke