In mice on a high-salt diet, a soy phospholipid fraction lowered blood pressure and improved object memory

What the research found

Study (mice). Hisayoshi Kubota, Akihiro Mouri, and colleagues at Fujita Health University, with Kazuhiro Kagotani of Tsuji Oil Mills, report in Neurochemistry International (2026; 197:106184; DOI 10.1016/j.neuint.2026.106184; online 14 May 2026). ScienceDaily ran it on 18 Oct 2026. Mice on a high-salt diet had higher blood pressure, less social interaction, and worse object-recognition memory, without a clear change in general movement or anxiety-like behavior. Adding LPC70, a soy lysolecithin in which lysophosphatidylcholine is more than 70 percent of the phospholipids, improved blood pressure, social interaction, and object memory. In kidney, the salt diet raised COX-2 and the PGE2 receptor EP3, and LPC70 reduced those rises. In prefrontal cortex, salt lowered the PGD2 receptor DP1, and LPC70 restored it without changing DP2. Tsuji Oil Mills funded the work and employs a coauthor. This is not a human trial and not a reason to start a supplement. Not medical advice. Not a substitute for a prescribed medicine.

Evidence level: Animal study. Results in animals or cells often don't carry over to people.

Read the original at Fujita Health University / Neurochemistry International