Human study · Supplements / medicine · 21 Sept 2026
In 342 midlife women, more added sugar tracked older GrimAge2 even on otherwise healthy diets
Source: UCSF Psychiatry
What the research found
Study (cross-sectional; JAMA Network Open 2024, recirculated 21 September 2026). Dorothy Chiu, Elissa Epel, Barbara Laraia and colleagues scored 342 Black and White women (mean age 39.2) on Mediterranean, AHEI, and an epigenetic-nutrient index plus added sugar. Better diet scores tracked younger GrimAge2; each extra gram of added sugar tracked older GrimAge2 even after diet quality. Cross-section, not a feeding trial. Educational nutrition notes, not a sugar-tax or supplement claim.
Evidence level: Human study. A study in people, but an association isn't proof of cause.
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