Human study · Supplements / medicine · 17 Sept 2026
Time-restricted eating was safe and shifted HD markers in a 12-week pilot of 20 people
Source: News-Medical
What the research found
Study (uncontrolled 12-week pilot). Russell Wells, Amie Hiller and Oregon Health & Science University colleagues report in Nature Metabolism (doi 10.1038/s42255-026-01612-x) on 20 adults with early-stage Huntington’s disease who ate in a self-chosen 6–8 hour window. They kept weight and lean mass, followed the window more than five days a week, improved 0.5 points on the composite Unified Huntington’s Disease Rating Scale (which typically falls ~1 point per year in early disease), and saw a 13% drop in blood neurofilament light plus better mitochondrial activity in blood cells. No comparison arm; HD is not Alzheimer’s. Educational nutrition notes, not a disease treatment or a fasting prescription.
Evidence level: Human study. A study in people, but an association isn't proof of cause.
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