Clinical trial · Supplements / medicine · 14 Sept 2026
Isocaloric 10-hour eating did not beat a 16-hour pattern for weight in a small feeding trial
Source: EurekAlert
What the research found
Study (randomized isocaloric feeding trial). Daisy Duan and Johns Hopkins colleagues report in Obesity (TRIM; doi 10.1002/oby.70270) on 39 adults with obesity and prediabetes or diet-controlled type 2 diabetes (mean age 60; 92% women; 92% Black; mean BMI 35.2). A 10-hour time-restricted window versus a 16-hour usual eating pattern for 12 weeks, with matched calories, produced similar modest weight loss (median 2.7% vs 2.5%). Inflammatory markers and hunger biology did not clearly favor TRE. Small, mostly older women; not a reason to start, stop, or replace diabetes medicine. Educational metabolic notes, not medical advice.
Evidence level: Clinical trial. This is among the stronger kinds of evidence, but one study rarely settles a question.
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