Human study · Supplements / medicine · 14 Sept 2026
Low vitamin D linked to more pain after breast cancer surgery
Source: ScienceDaily
What the research found
Study (observational). Abdelhady and colleagues at Fayoum University Hospital followed 184 women having unilateral modified radical mastectomy (mean ages about 42–44). Those with vitamin D below 30 nmol/L were three times more likely to report moderate-to-severe pain in the first 24 hours and used more tramadol (about 112 mg) than the sufficient group; intraoperative fentanyl was only modestly higher. No one scored severe pain (≥7/10). Single-center, not a supplementation trial, and not proof that vitamin D causes pain. Educational notes, not a prescription to start vitamin D before surgery.
Evidence level: Human study. A study in people, but an association isn't proof of cause.
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